Fragment: affc493b6cbff08efa3d6c8988a9282d
SMILES: [16*]c1ccc(O)cc1
Source Method: Murcko+BRICS
Appears In Molecules
| ID | Name | SMILES | Link |
|---|---|---|---|
| CHEMBL1082 | CHEMBL1082 | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O | View |
| CHEMBL1116 | CHEMBL1116 | Cl.O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 | View |
| CHEMBL112 | CHEMBL112 | CC(=O)Nc1ccc(O)cc1 | View |
| CHEMBL411 | CHEMBL411 | CC/C(=C(/CC)c1ccc(O)cc1)c1ccc(O)cc1 | View |
| CHEMBL44 | CHEMBL44 | O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 | View |
| CHEMBL441738 | CHEMBL441738 | CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | View |
| CHEMBL44426 | CHEMBL44426 | Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 | View |
| CHEMBL46740 | CHEMBL46740 | Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12 | View |
| CHEMBL81 | CHEMBL81 | O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 | View |
| CHEMBL8145 | CHEMBL8145 | O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12 | View |
Associated Targets
| Target | Organism | Link |
|---|---|---|
| Serine/threonine-protein kinase OSR1 | Homo sapiens | View |
| Bromodomain-containing protein 4 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-1 | Homo sapiens | View |
| Serine/threonine-protein kinase VRK1 | Homo sapiens | View |
| ATP-dependent DNA helicase Q1 | Homo sapiens | View |
| Bloom syndrome protein | Homo sapiens | View |
| Thrombopoietin | Homo sapiens | View |
| Geminin | Homo sapiens | View |
| Bromodomain-containing protein 2 | Homo sapiens | View |
| Peripheral myelin protein 22 | Homo sapiens | View |
| Serine/threonine-protein kinase VRK2 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens | View |
| Nuclear receptor ROR-gamma | Homo sapiens | View |
| Chromobox protein homolog 1 | Homo sapiens | View |
| ATPase family AAA domain-containing protein 5 | Homo sapiens | View |
| M-phase phosphoprotein 8 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens | View |
| Solute carrier family 15 member 2 | Homo sapiens | View |
| Multidrug resistance-associated protein 4 | Homo sapiens | View |
| Sulfotransferase 1A1 | Homo sapiens | View |
| Sulfotransferase 1C4 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-7 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-8 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-9 | Homo sapiens | View |
| UDP-glucuronosyltransferase 1-10 | Homo sapiens | View |
| 78 kDa glucose-regulated protein | Homo sapiens | View |
| Ataxin-2 | Homo sapiens | View |
| Ubiquitin carboxyl-terminal hydrolase 1 | Homo sapiens | View |
| Regulator of G-protein signaling 4 | Homo sapiens | View |
| Bromodomain-containing protein 3 | Homo sapiens | View |
| Cyclin-dependent kinase 4/cyclin D1 | Homo sapiens | View |
| Cyclin-dependent kinase 1/cyclin B1 | Homo sapiens | View |
| Runt-related transcription factor 1/Core-binding factor subunit beta | Homo sapiens | View |
| Estrogen receptor | Homo sapiens | View |
| Cyclooxygenase | Homo sapiens | View |
| Monoamine oxidase | Homo sapiens | View |
| Sodium channel alpha subunits; brain (Types I, II, III) | Homo sapiens | View |
| Tyrosine-protein kinase ABL | Homo sapiens | View |
| Glutaminase kidney isoform, mitochondrial | Homo sapiens | View |
| Rac GTPase-activating protein 1 | Homo sapiens | View |
| Cytochrome c | Homo sapiens | View |
| Delta(24)-sterol reductase | Homo sapiens | View |
| Complement C5 | Homo sapiens | View |
| Myoglobin | Homo sapiens | View |
| Transcription intermediary factor 1-alpha | Homo sapiens | View |
| Interleukin-6 receptor subunit beta | Homo sapiens | View |
| Peregrin | Homo sapiens | View |
| IL6Ralpha/GP130 | Homo sapiens | View |
| LIFR/GP130 | Homo sapiens | View |
| DNMT3A2/3L complex | Homo sapiens | View |
| Inactive serine/threonine-protein kinase VRK3 | Homo sapiens | View |
| KOPN-8 | Homo sapiens | View |
| LN-229 | Homo sapiens | View |
| LNCaP C4-2 | Homo sapiens | View |
| SEM | Homo sapiens | View |
| SUP-B15 | Homo sapiens | View |
| THLE-2 | Homo sapiens | View |
| UoC-B1 | Homo sapiens | View |
| Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | Homo sapiens | View |
| Cholesterol 24-hydroxylase | Homo sapiens | View |
| COLO 201 | Homo sapiens | View |
| Cytochrome P450 | Homo sapiens | View |
| HepaRG | Homo sapiens | View |
| Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 | Homo sapiens | View |
| Fibroblast | Homo sapiens | View |
| Neutrophil | Homo sapiens | View |
| Estradiol 17-beta-dehydrogenase 1 | Homo sapiens | View |
| Phosphodiesterase 6A | Homo sapiens | View |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens | View |
| Cystic fibrosis transmembrane conductance regulator | Homo sapiens | View |
| Interleukin-8 receptor A | Homo sapiens | View |
| Protein kinase C alpha | Homo sapiens | View |
| MAP kinase ERK1 | Homo sapiens | View |
| Tyrosine-protein kinase FYN | Homo sapiens | View |
| Melanocortin receptor 1 | Homo sapiens | View |
| Phospholipase D2 | Homo sapiens | View |
| DNA topoisomerase II beta | Homo sapiens | View |
| Multidrug resistance-associated protein 1 | Homo sapiens | View |
| Aldehyde oxidase | Homo sapiens | View |
| Leukocyte common antigen | Homo sapiens | View |
| Carbonic anhydrase XII | Homo sapiens | View |
| Histone deacetylase 7 | Homo sapiens | View |
| Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | Homo sapiens | View |
| Testis-specific androgen-binding protein | Homo sapiens | View |
| Serine/threonine-protein kinase AKT | Homo sapiens | View |
| Estrogen sulfotransferase | Homo sapiens | View |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens | View |
| Carbonic anhydrase IV | Homo sapiens | View |
| Estradiol 17-beta-dehydrogenase 2 | Homo sapiens | View |
| Cytochrome P450 2E1 | Homo sapiens | View |
| Cytochrome P450 2A6 | Homo sapiens | View |
| Cytochrome P450 2B6 | Homo sapiens | View |
| LXR-beta | Homo sapiens | View |
| Serine/threonine-protein kinase 16 | Homo sapiens | View |
| Dual specificity protein kinase CLK1 | Homo sapiens | View |
| Serine/threonine-protein kinase PCTAIRE-1 | Homo sapiens | View |
| CaM kinase I gamma | Homo sapiens | View |
| CaM-kinase kinase beta | Homo sapiens | View |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens | View |
| Serine/threonine-protein kinase 2 | Homo sapiens | View |
| TRAF2- and NCK-interacting kinase | Homo sapiens | View |
| AGS | Homo sapiens | View |
| Breast carcinoma cell | Homo sapiens | View |
| BT-20 | Homo sapiens | View |
| BXPC-3 | Homo sapiens | View |
| HT-1080 | Homo sapiens | View |
| MCF-12A | Homo sapiens | View |
| MCF7 | Homo sapiens | View |
| MG-63 | Homo sapiens | View |
| MKN-1 | Homo sapiens | View |
| MKN-28 | Homo sapiens | View |
| MKN-7 | Homo sapiens | View |
| MKN-74 | Homo sapiens | View |
| MOLT-3 | Homo sapiens | View |
| PANC-1 | Homo sapiens | View |
| Raji | Homo sapiens | View |
| SGC-7901 | Homo sapiens | View |
| St-4 | Homo sapiens | View |
| T98G | Homo sapiens | View |
| U2OS | Homo sapiens | View |
| U-937 | Homo sapiens | View |
| COLO357 | Homo sapiens | View |
| WiDr | Homo sapiens | View |
| Monocyte | Homo sapiens | View |
| HUVEC | Homo sapiens | View |
| Ishikawa | Homo sapiens | View |
| KM-20L2 | Homo sapiens | View |
| Monoglyceride lipase | Homo sapiens | View |
| Gastric inhibitory polypeptide receptor | Homo sapiens | View |
| Hypoxia-inducible factor 1 alpha | Homo sapiens | View |
| Vasoactive intestinal polypeptide receptor 1 | Homo sapiens | View |
| PDZ-binding kinase | Homo sapiens | View |
| High-affinity choline transporter | Homo sapiens | View |
| Aldo-keto-reductase family 1 member C3 | Homo sapiens | View |
| CWR22R | Homo sapiens | View |
| Cytochrome P450 2J2 | Homo sapiens | View |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens | View |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens | View |
| Myotonin-protein kinase | Homo sapiens | View |
| ATP-binding cassette sub-family G member 2 | Homo sapiens | View |
| Protein disulfide-isomerase | Homo sapiens | View |
| Nuclear receptor subfamily 1 group I member 3 | Homo sapiens | View |
| DNA polymerase eta | Homo sapiens | View |
| Mitogen-activated protein kinase 6 | Homo sapiens | View |
| Serine/threonine-protein kinase 25 | Homo sapiens | View |
| Carbonyl reductase [NADPH] 1 | Homo sapiens | View |
| Solute carrier family 22 member 1 | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | View |
| Serine/threonine-protein kinase RIO2 | Homo sapiens | View |
| Carbonyl reductase [NADPH] 3 | Homo sapiens | View |
| Ubiquitin-conjugating enzyme E2 N | Homo sapiens | View |
| Cyclin-dependent kinase-like 1 | Homo sapiens | View |
| Hepatocyte | Homo sapiens | View |
| Liver | Homo sapiens | View |
| Plasma | Homo sapiens | View |
| Skin | Homo sapiens | View |
| Bile salt export pump | Homo sapiens | View |
| Aldo-keto reductase family 1 member B10 | Homo sapiens | View |
| 3-keto-steroid reductase | Homo sapiens | View |
| UDP-glucose 4-epimerase | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | View |
| UDP-glucuronosyltransferase 2B4 | Homo sapiens | View |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens | View |
| UDP-glucuronosyltransferase 2B15 | Homo sapiens | View |
| Serine/threonine-protein kinase 38 | Homo sapiens | View |
| Nuclear factor erythroid 2-related factor 2 | Homo sapiens | View |
| Maltase-glucoamylase | Homo sapiens | View |
| Tyrosine-protein kinase ABL | Homo sapiens | View |
| Epidermal growth factor receptor erbB1 | Homo sapiens | View |
| Adenosine deaminase | Homo sapiens | View |
| Estrogen receptor alpha | Homo sapiens | View |
| HMG-CoA reductase | Homo sapiens | View |
| Aldehyde dehydrogenase | Homo sapiens | View |
| DNA topoisomerase II alpha | Homo sapiens | View |
| Histamine H2 receptor | Homo sapiens | View |
| Calcitonin receptor | Homo sapiens | View |
| Xanthine dehydrogenase | Homo sapiens | View |
| Estrogen receptor beta | Homo sapiens | View |
| Equilibrative nucleoside transporter 1 | Homo sapiens | View |
| Cysteinyl leukotriene receptor 1 | Homo sapiens | View |
| Alpha-2b adrenergic receptor | Homo sapiens | View |
| Aldose reductase | Homo sapiens | View |
| Platelet activating factor receptor | Homo sapiens | View |
| Ornithine decarboxylase | Homo sapiens | View |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens | View |
| Interleukin-8 | Homo sapiens | View |
| 5-lipoxygenase activating protein | Homo sapiens | View |
| Estrogen-related receptor alpha | Homo sapiens | View |
| Carbonic anhydrase III | Homo sapiens | View |
| Melanocortin receptor 4 | Homo sapiens | View |
| Serum paraoxonase/arylesterase 1 | Homo sapiens | View |
| Cytochrome P450 2C8 | Homo sapiens | View |
| Carbonic anhydrase VI | Homo sapiens | View |
| Fatty acid binding protein adipocyte | Homo sapiens | View |
| GABA-B receptor 1 | Homo sapiens | View |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens | View |
| Tyrosine-protein kinase SRC | Homo sapiens | View |
| Neuropeptide Y receptor type 2 | Homo sapiens | View |
| Cyclin-dependent kinase 6 | Homo sapiens | View |
| Cathepsin G | Homo sapiens | View |
| Oligopeptide transporter small intestine isoform | Homo sapiens | View |
| C-C chemokine receptor type 4 | Homo sapiens | View |
| AMP-activated protein kinase, alpha-2 subunit | Homo sapiens | View |
| Neuronal acetylcholine receptor protein alpha-4 subunit | Homo sapiens | View |
| Sialidase 2 | Homo sapiens | View |
| Angiotensin II type 2 (AT-2) receptor | Homo sapiens | View |
| Aryl hydrocarbon receptor | Homo sapiens | View |
| Serum albumin | Homo sapiens | View |
| Salivary alpha-amylase | Homo sapiens | View |
| Cerebroside-sulfatase | Homo sapiens | View |
| Interleukin-8 receptor B | Homo sapiens | View |
| Corticotropin releasing factor receptor 2 | Homo sapiens | View |
| HLA class I histocompatibility antigen A-3 | Homo sapiens | View |
| Serine/threonine-protein kinase PIM1 | Homo sapiens | View |
| Phospholipase D1 | Homo sapiens | View |
| Tyrosine-protein kinase SYK | Homo sapiens | View |
| Melanocortin receptor 3 | Homo sapiens | View |
| Melanocortin receptor 5 | Homo sapiens | View |
| Carbonic anhydrase VB | Homo sapiens | View |
| Carbonic anhydrase VA | Homo sapiens | View |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens | View |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens | View |
| Carbonic anhydrase VII | Homo sapiens | View |
| Motilin receptor | Homo sapiens | View |
| Carbonic anhydrase XIV | Homo sapiens | View |
| Cytochrome P450 1A1 | Homo sapiens | View |
| Aldehyde dehydrogenase 1A1 | Homo sapiens | View |
| 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Homo sapiens | View |
| Estrogen-related receptor beta | Homo sapiens | View |
| Estrogen-related receptor gamma | Homo sapiens | View |
| LXR-alpha | Homo sapiens | View |