Nuclear receptor subfamily 1 group I member 3
Target ID: CHEMBL5503
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| SUNITINIB | CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C | IC50: 80.0 nM |  |
| ACETAMINOPHEN | CC(=O)Nc1ccc(O)cc1 | Vdss: 0.95 L.kg-1 |  |
| AMOXICILLIN | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O | MIC: 0.021 ug.mL-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N[5*] | 7.1 | 58 |  |
| [7*]C1C(=O)Nc2ccc(F)cc21 | 7.1 | 39 |  |
| [4*]CC | 7.1 | 39 |  |
| [5*]N([5*])[5*] | 7.1 | 39 |  |
| [7*]C[8*] | 7.1 | 39 |  |