Aryl hydrocarbon receptor
Target ID: CHEMBL3201
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| GENISTEIN | O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 | IC50: 1000.0 nM |  |
| AMITRAZ | Cc1ccc(/N=C/N(C)/C=N/c2ccc(C)cc2C)c(C)c1 | Potency: 0.9 nM |  |
| DAIDZEIN | O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12 | Suppression: 22.0 % |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1ccc(O)cc1 | 6.0 | 68 |  |
| O=c1c(-c2ccccc2)coc2ccccc12 | 6.0 | 68 |  |
| [16*]c1coc2cc(O)cc(O)c2c1=O | 6.0 | 39 |  |
| [16*]c1coc2cc(O)ccc2c1=O | None | 29 |  |
| C(=N/c1ccccc1)\N/C=N/c1ccccc1 | 9.05 | 19 |  |