Regulator of G-protein signaling 4
Target ID: CHEMBL1795091
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| BRIMONIDINE | Brc1c(NC2=NCCN2)ccc2nccnc12 | pC25: 1.55 uM kg-1 |  |
| DIETHYLSTILBESTROL | CC/C(=C(/CC)c1ccc(O)cc1)c1ccc(O)cc1 | EC50: 9.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [7*]C([8*])CC | 8.05 | 30 |  |
| [16*]c1ccc(O)cc1 | 8.05 | 30 |  |
| C(=Cc1ccccc1)c1ccccc1 | 8.05 | 30 |  |
| [5*]NC1=NCCN1 | None | 14 |  |
| c1cnc2cc(NC3=NCCN3)ccc2n1 | None | 14 |  |