Fibroblast
Target ID: CHEMBL5314315
Organism: Homo sapiens
Type: CELL-LINE
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| SELICICLIB | CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 | IC50: 450.0 nM |  |
| QUERCETIN | O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 | IC50: 32870.0 nM |  |
| BAZEDOXIFENE | Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12 | IC50: 23.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N[5*] | 6.35 | 39 |  |
| [4*]C[8*] | 6.35 | 39 |  |
| c1ccc(CNc2ncnc3[nH]cnc23)cc1 | 6.35 | 39 |  |
| [8*]C(C)C | 6.35 | 39 |  |
| [16*]c1ccccc1 | 6.35 | 39 |  |