Ubiquitin-conjugating enzyme E2 N
Target ID: CHEMBL6089
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| RALOXIFENE HYDROCHLORIDE | Cl.O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 | IC50: 0.4 nM |  |
| TAMOXIFEN | CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 | IC50: 6750.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [4*]CC[4*] | 7.32 | 57 |  |
| [16*]c1ccc([16*])cc1 | 7.32 | 57 |  |
| [3*]O[3*] | 7.32 | 57 |  |
| [14*]c1sc2cc(O)ccc2c1[16*] | 9.4 | 29 |  |
| O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccccc2)sc2ccccc12 | 9.4 | 29 |  |