DNA polymerase eta
Target ID: CHEMBL5542
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| AMPICILLIN | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O | MIC: 5.0 ug.mL-1 |  |
| AMOXICILLIN | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O | MIC: 0.021 ug.mL-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| O=C(Cc1ccccc1)N[C@@H]1C(=O)N2CCS[C@H]12 | None | 17 |  |
| [5*]N[5*] | None | 17 |  |
| [6*]C(=O)O | None | 17 |  |
| [13*][C@@H]1N2C(=O)[C@@H]([15*])[C@H]2SC1(C)C | None | 17 |  |
| [1*]C(=O)[C@@H]([8*])N | None | 17 |  |