Runt-related transcription factor 1/Core-binding factor subunit beta
Target ID: CHEMBL2093862
Organism: Homo sapiens
Type: PROTEIN-PROTEIN INTERACTION
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| MIFEPRISTONE | CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)C)cc3)C[C@@]21C | IC50: 0.028 nM |  |
| LEVODOPA | N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O | IC50: 900000.0 nM |  |
| RALOXIFENE HYDROCHLORIDE | Cl.O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 | IC50: 0.4 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1ccc([16*])cc1 | 9.99 | 60 |  |
| [8*]C[C@H](N)C(=O)O | 3.05 | 39 |  |
| c1ccccc1 | 3.05 | 39 |  |
| [16*]c1ccc(O)c(O)c1 | 3.05 | 39 |  |
| [5*]N(C)C | 10.55 | 31 |  |