Fragment: b3c49bd868216229c96e3f4cdd9791a7
SMILES: [16*]c1ccc(F)cc1
Source Method: Murcko+BRICS
Appears In Molecules
| ID | Name | SMILES | Link |
|---|---|---|---|
| CHEMBL1496 | CHEMBL1496 | CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O | View |
| CHEMBL2220442 | CHEMBL2220442 | CC(C)n1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21 | View |
| CHEMBL296419 | CHEMBL296419 | COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 | View |
| CHEMBL30008 | CHEMBL30008 | Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C/c3ccccc3)CC2)cc1 | View |
Associated Targets
| Target | Organism | Link |
|---|---|---|
| Nuclear receptor subfamily 4 group A member 1 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens | View |
| Chromobox protein homolog 1 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens | View |
| Multidrug and toxin extrusion protein 1 | Homo sapiens | View |
| Multidrug resistance-associated protein 4 | Homo sapiens | View |
| Ataxin-2 | Homo sapiens | View |
| Voltage-gated L-type calcium channel | Homo sapiens | View |
| Sodium channel alpha subunits; brain (Types I, II, III) | Homo sapiens | View |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens | View |
| Polycomb protein EED | Homo sapiens | View |
| DB | Homo sapiens | View |
| Sigma intracellular receptor 2 | Homo sapiens | View |
| Protein patched homolog 1 | Homo sapiens | View |
| Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 | Homo sapiens | View |
| Phosphodiesterase 6A | Homo sapiens | View |
| Sphingomyelin phosphodiesterase | Homo sapiens | View |
| Interleukin-8 receptor A | Homo sapiens | View |
| MAP kinase ERK1 | Homo sapiens | View |
| Heparanase | Homo sapiens | View |
| Tyrosine-protein kinase FYN | Homo sapiens | View |
| Leukocyte common antigen | Homo sapiens | View |
| Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | Homo sapiens | View |
| Cytochrome P450 3A4 | Homo sapiens | View |
| Cytochrome P450 2E1 | Homo sapiens | View |
| Cytochrome P450 2A6 | Homo sapiens | View |
| Cytochrome P450 2B6 | Homo sapiens | View |
| RD | Homo sapiens | View |
| HepG2 | Homo sapiens | View |
| Voltage-gated T-type calcium channel alpha-1G subunit | Homo sapiens | View |
| Voltage-gated T-type calcium channel alpha-1I subunit | Homo sapiens | View |
| Bile acid transporter | Homo sapiens | View |
| Gastric inhibitory polypeptide receptor | Homo sapiens | View |
| Vasoactive intestinal polypeptide receptor 1 | Homo sapiens | View |
| NAD-dependent deacetylase sirtuin 3 | Homo sapiens | View |
| Cytochrome P450 2J2 | Homo sapiens | View |
| Nuclear receptor subfamily 4 group A member 2 | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | View |
| Hepatocyte | Homo sapiens | View |
| Bile salt export pump | Homo sapiens | View |
| Glycine receptor subunit alpha-1 | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | View |
| H4 | Homo sapiens | View |
| Voltage-gated T-type calcium channel alpha-1H subunit | Homo sapiens | View |
| HMG-CoA reductase | Homo sapiens | View |
| Histamine H2 receptor | Homo sapiens | View |
| Somatostatin receptor 2 | Homo sapiens | View |
| Calcitonin receptor | Homo sapiens | View |
| Histamine H1 receptor | Homo sapiens | View |
| HERG | Homo sapiens | View |
| Voltage-gated L-type calcium channel alpha-1C subunit | Homo sapiens | View |
| Equilibrative nucleoside transporter 1 | Homo sapiens | View |
| Cysteinyl leukotriene receptor 1 | Homo sapiens | View |
| Alpha-2b adrenergic receptor | Homo sapiens | View |
| Platelet activating factor receptor | Homo sapiens | View |
| Cytochrome P450 2C8 | Homo sapiens | View |
| Somatostatin receptor 4 | Homo sapiens | View |
| GABA-B receptor 1 | Homo sapiens | View |
| Neuropeptide Y receptor type 2 | Homo sapiens | View |
| Cathepsin G | Homo sapiens | View |
| Voltage-gated N-type calcium channel alpha-1B subunit | Homo sapiens | View |
| C-C chemokine receptor type 4 | Homo sapiens | View |
| Phosphodiesterase 6D | Homo sapiens | View |
| Neuronal acetylcholine receptor protein alpha-4 subunit | Homo sapiens | View |
| Angiotensin II type 2 (AT-2) receptor | Homo sapiens | View |
| Interleukin-8 receptor B | Homo sapiens | View |
| Corticotropin releasing factor receptor 2 | Homo sapiens | View |
| HLA class I histocompatibility antigen A-3 | Homo sapiens | View |
| Motilin receptor | Homo sapiens | View |
| Somatostatin receptor 3 | Homo sapiens | View |
| Somatostatin receptor 5 | Homo sapiens | View |
| P-glycoprotein 1 | Homo sapiens | View |