Bile acid transporter
Target ID: CHEMBL5287
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| FUROSEMIDE | NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl | Ki: 100000.0 nM |  |
| FLUVASTATIN | CC(C)n1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21 | IC50: 28.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1cc(Cl)c(S(N)(=O)=O)cc1[16*] | 4.0 | 24 |  |
| [14*]c1ccco1 | 4.0 | 24 |  |
| [5*]N[5*] | 4.0 | 24 |  |
| [4*]C[8*] | 4.0 | 24 |  |
| c1ccc(NCc2ccco2)cc1 | 4.0 | 24 |  |