Histamine H1 receptor
Target ID: CHEMBL231
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| HISTAMINE | NCCc1c[nH]cn1 | KA: 2.0 uM |  |
| ASTEMIZOLE | COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 | Binding energy: 11.3 kCal mol-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [8*]CCN | None | 36 |  |
| c1c[nH]cn1 | None | 36 |  |
| [14*]c1c[nH]cn1 | None | 36 |  |
| c1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccccc3)CC2)cc1 | None | 6 |  |
| [16*]c1ccc([16*])cc1 | None | 6 |  |