Phosphodiesterase 6D
Target ID: CHEMBL3860
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ROSUVASTATIN | CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O | Ki: 0.9 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1ccc(F)cc1 | 9.05 | 19 |  |
| [5*]N([5*])C | 9.05 | 19 |  |
| [7*]C[C@@H](O)C[C@@H](O)CC(=O)O | 9.05 | 19 |  |
| [8*]C(C)C | 9.05 | 19 |  |
| [14*]c1nc([14*])c([16*])c([14*])n1 | 9.05 | 19 |  |