Fragment: ba19992b82636403e3b9e03138720e4a
SMILES: O=c1[nH]c(=O)c2[nH]cnc2[nH]1
Source Method: Murcko+BRICS
Appears In Molecules
| ID | Name | SMILES | Link |
|---|---|---|---|
| CHEMBL113 | CHEMBL113 | Cn1c(=O)c2c(ncn2C)n(C)c1=O | View |
| CHEMBL190 | CHEMBL190 | Cn1c(=O)c2[nH]cnc2n(C)c1=O | View |
| CHEMBL37390 | CHEMBL37390 | CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C | View |
Associated Targets
| Target | Organism | Link |
|---|---|---|
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens | View |
| Nuclear receptor ROR-gamma | Homo sapiens | View |
| Chromobox protein homolog 1 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens | View |
| Multidrug resistance-associated protein 4 | Homo sapiens | View |
| Solute carrier family 22 member 7 | Homo sapiens | View |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens | View |
| Phosphodiesterase 4 | Homo sapiens | View |
| GABA-A receptor; anion channel | Homo sapiens | View |
| Phosphodiesterase 3 | Homo sapiens | View |
| Adenosine A2 receptor | Homo sapiens | View |
| Phosphodiesterase 1 | Homo sapiens | View |
| Adenosine receptors; A1 & A3 | Homo sapiens | View |
| Adenosine receptors; A1 & A2 | Homo sapiens | View |
| Sodium channel alpha subunits; brain (Types I, II, III) | Homo sapiens | View |
| Adenosine receptor | Homo sapiens | View |
| Retinal dehydrogenase 2 | Homo sapiens | View |
| Transmembrane domain-containing protein TMIGD3 | Homo sapiens | View |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens | View |
| Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | Homo sapiens | View |
| Phosphodiesterase 6A | Homo sapiens | View |
| Interleukin-8 receptor A | Homo sapiens | View |
| MAP kinase ERK1 | Homo sapiens | View |
| Tyrosine-protein kinase FYN | Homo sapiens | View |
| Brain adenylate cyclase 1 | Homo sapiens | View |
| Phosphodiesterase 7A | Homo sapiens | View |
| Leukocyte common antigen | Homo sapiens | View |
| Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | Homo sapiens | View |
| Ryanodine receptor 2 | Homo sapiens | View |
| Cytochrome P450 2E1 | Homo sapiens | View |
| Cytochrome P450 2A6 | Homo sapiens | View |
| Cytochrome P450 2B6 | Homo sapiens | View |
| Serine-protein kinase ATR | Homo sapiens | View |
| Caco-2 | Homo sapiens | View |
| Gastric inhibitory polypeptide receptor | Homo sapiens | View |
| Vasoactive intestinal polypeptide receptor 1 | Homo sapiens | View |
| Intestinal alkaline phosphatase | Homo sapiens | View |
| Solute carrier family 22 member 1 | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | View |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens | View |
| Hepatocyte | Homo sapiens | View |
| Skin | Homo sapiens | View |
| Bile salt export pump | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | View |
| Phospholipase A-2-activating protein | Homo sapiens | View |
| Phosphodiesterase 5A | Homo sapiens | View |
| HMG-CoA reductase | Homo sapiens | View |
| Aldehyde dehydrogenase | Homo sapiens | View |
| Histamine H2 receptor | Homo sapiens | View |
| Monoamine oxidase B | Homo sapiens | View |
| Adenosine A1 receptor | Homo sapiens | View |
| Calcitonin receptor | Homo sapiens | View |
| Cysteinyl leukotriene receptor 1 | Homo sapiens | View |
| Alpha-2b adrenergic receptor | Homo sapiens | View |
| Platelet activating factor receptor | Homo sapiens | View |
| Adenosine A2a receptor | Homo sapiens | View |
| Adenosine A2b receptor | Homo sapiens | View |
| Adenosine A3 receptor | Homo sapiens | View |
| Bradykinin B2 receptor | Homo sapiens | View |
| DNA-dependent protein kinase | Homo sapiens | View |
| Aldehyde dehydrogenase X | Homo sapiens | View |
| Cytochrome P450 2C8 | Homo sapiens | View |
| GABA-B receptor 1 | Homo sapiens | View |
| Neuropeptide Y receptor type 2 | Homo sapiens | View |
| Cathepsin G | Homo sapiens | View |
| C-C chemokine receptor type 4 | Homo sapiens | View |
| Phosphodiesterase 2A | Homo sapiens | View |
| Neuronal acetylcholine receptor protein alpha-4 subunit | Homo sapiens | View |
| Angiotensin II type 2 (AT-2) receptor | Homo sapiens | View |
| Serum albumin | Homo sapiens | View |
| Cerebroside-sulfatase | Homo sapiens | View |
| Interleukin-8 receptor B | Homo sapiens | View |
| Corticotropin releasing factor receptor 2 | Homo sapiens | View |
| Prion protein | Homo sapiens | View |
| Aldehyde dehydrogenase dimeric NADP-preferring | Homo sapiens | View |
| Aldehyde dehydrogenase 1A3 | Homo sapiens | View |
| Guanine deaminase | Homo sapiens | View |
| Phosphodiesterase 1C | Homo sapiens | View |
| Legumain | Homo sapiens | View |
| Muscle glycogen phosphorylase | Homo sapiens | View |