Muscle glycogen phosphorylase
Target ID: CHEMBL3526
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| CAFFEINE | Cn1c(=O)c2c(ncn2C)n(C)c1=O | Vdss: 0.61 L.kg-1 |  |
| ALVOCIDIB | CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 | IC50: 330.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| O=c1cc(-c2ccccc2)oc2c(C3CCNCC3)cccc12 | 6.48 | 39 |  |
| [15*][C@H]1CCN(C)C[C@H]1O | 6.48 | 39 |  |
| [14*]c1cc(=O)c2c(O)cc(O)c([16*])c2o1 | 6.48 | 39 |  |
| [16*]c1ccccc1Cl | 6.48 | 39 |  |
| Cn1c(=O)c2c(ncn2C)n(C)c1=O | None | 5 |  |