Fragment: 8463c9c1ed07daca717b015aaa3bbda4
SMILES: O=c1[nH]c(-c2cccc(S(=O)(=O)N3CCNCC3)c2)nc2cn[nH]c12
Source Method: Murcko+BRICS
Appears In Molecules
| ID | Name | SMILES | Link |
|---|---|---|---|
| CHEMBL1737 | CHEMBL1737 | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12.O=C(O)CC(O)(CC(=O)O)C(=O)O | View |
| CHEMBL192 | CHEMBL192 | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 | View |
| CHEMBL53538 | CHEMBL53538 | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(CCO)CC4)ccc3OCC)nc12 | View |
Associated Targets
| Target | Organism | Link |
|---|---|---|
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens | View |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens | View |
| Multidrug resistance-associated protein 4 | Homo sapiens | View |
| Multidrug resistance-associated protein 5 | Homo sapiens | View |
| Multidrug resistance-associated protein 7 | Homo sapiens | View |
| ATP-binding cassette sub-family C member 11 | Homo sapiens | View |
| Phosphodiesterase 4 | Homo sapiens | View |
| Phosphodiesterase 3 | Homo sapiens | View |
| Phosphodiesterase 1 | Homo sapiens | View |
| Phosphodiesterases; PDE5 & PDE6 | Homo sapiens | View |
| Phosphodiesterase, PDE1/PDE5 | Homo sapiens | View |
| Phosphodiesterase 6 | Homo sapiens | View |
| Phosphodiesterase 7 | Homo sapiens | View |
| Phosphodiesterase 2 and 5 (PDE2 and PDE5) | Homo sapiens | View |
| Phosphodiesterase 4 and 5 (PDE4 and PDE5) | Homo sapiens | View |
| Phosphodiesterase 3 and 5 (PDE3 and PDE5) | Homo sapiens | View |
| Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) | Homo sapiens | View |
| Phosphodiesterase 8 | Homo sapiens | View |
| Whole blood | Homo sapiens | View |
| THLE-2 | Homo sapiens | View |
| PDE5A/PDE6C | Homo sapiens | View |
| Sodium channel protein type V alpha subunit | Homo sapiens | View |
| Phosphodiesterase 6A | Homo sapiens | View |
| Phosphodiesterase 7A | Homo sapiens | View |
| Carbonic anhydrase XII | Homo sapiens | View |
| Phosphodiesterase 11A | Homo sapiens | View |
| Carbonic anhydrase IV | Homo sapiens | View |
| Phosphodiesterase 9A | Homo sapiens | View |
| Homo sapiens | Homo sapiens | View |
| Phosphodiesterase 8A | Homo sapiens | View |
| Phosphodiesterase 10A | Homo sapiens | View |
| Gastric inhibitory polypeptide receptor | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | View |
| Hepatocyte | Homo sapiens | View |
| Serum | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | View |
| Phosphodiesterase 5A | Homo sapiens | View |
| HERG | Homo sapiens | View |
| Voltage-gated L-type calcium channel alpha-1C subunit | Homo sapiens | View |
| Phosphodiesterase 3A | Homo sapiens | View |
| Equilibrative nucleoside transporter 1 | Homo sapiens | View |
| Phosphodiesterase 4A | Homo sapiens | View |
| Carbonic anhydrase III | Homo sapiens | View |
| Phosphodiesterase 1A | Homo sapiens | View |
| Carbonic anhydrase VI | Homo sapiens | View |
| GABA-B receptor 1 | Homo sapiens | View |
| Phosphodiesterase 2A | Homo sapiens | View |
| Corticotropin releasing factor receptor 2 | Homo sapiens | View |
| Carbonic anhydrase VB | Homo sapiens | View |
| Carbonic anhydrase VA | Homo sapiens | View |
| Carbonic anhydrase VII | Homo sapiens | View |
| Motilin receptor | Homo sapiens | View |
| Carbonic anhydrase XIV | Homo sapiens | View |
| Voltage-gated potassium channel subunit Kv4.3 | Homo sapiens | View |
| Phosphodiesterase 4D | Homo sapiens | View |
| Phosphodiesterase 6C | Homo sapiens | View |