Phosphodiesterase 2 and 5 (PDE2 and PDE5)
Target ID: CHEMBL2111470
Organism: Homo sapiens
Type: SELECTIVITY GROUP
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| SILDENAFIL | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 | Pc: 87000000.0 cm s-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [12*]S(=O)(=O)c1ccc([16*])c([16*])c1 | None | 39 |  |
| O=c1[nH]c(-c2cccc(S(=O)(=O)N3CCNCC3)c2)nc2cn[nH]c12 | None | 39 |  |
| [8*]CCC | None | 39 |  |
| [5*]N1CCN(C)CC1 | None | 39 |  |
| [4*]CC | None | 39 |  |