Fragment: 7d45210b2904075a7a6eab93095a206e
SMILES: [5*]NC(=N)N
Source Method: Murcko+BRICS
Appears In Molecules
| ID | Name | SMILES | Link |
|---|---|---|---|
| CHEMBL114715 | CHEMBL114715 | N=C(N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(=O)O | View |
| CHEMBL1166 | CHEMBL1166 | CC1CNc2c(cccc2S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)N2CC[C@@H](C)C[C@@H]2C(=O)O)C1 | View |
| CHEMBL273264 | CHEMBL273264 | N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)cc1 | View |
| CHEMBL441738 | CHEMBL441738 | CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C | View |
| CHEMBL87563 | CHEMBL87563 | CCOC(=O)c1ccc(OC(=O)CCCCCNC(=N)N)cc1 | View |
| CHEMBL945 | CHEMBL945 | N=C(N)NC(=O)c1nc(Cl)c(N)nc1N | View |
Associated Targets
| Target | Organism | Link |
|---|---|---|
| Amiloride-sensitive cation channel 2, neuronal | Homo sapiens | View |
| Amiloride-sensitive sodium channel subunit beta | Homo sapiens | View |
| Amiloride-sensitive sodium channel subunit gamma | Homo sapiens | View |
| Solute carrier family 22 member 2 | Homo sapiens | View |
| Multidrug and toxin extrusion protein 1 | Homo sapiens | View |
| Multidrug and toxin extrusion protein 2 | Homo sapiens | View |
| Serine protease hepsin | Homo sapiens | View |
| Menin/Histone-lysine N-methyltransferase MLL | Homo sapiens | View |
| Collagenase | Homo sapiens | View |
| Thrombin & trypsin | Homo sapiens | View |
| Thrombin and urokinase-type plasminogen activator | Homo sapiens | View |
| Thrombin and coagulation factor X | Homo sapiens | View |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens | View |
| Hepatocyte growth factor activator | Homo sapiens | View |
| Interleukin-8 receptor A | Homo sapiens | View |
| MAP kinase ERK1 | Homo sapiens | View |
| Complement C1r | Homo sapiens | View |
| Tyrosine-protein kinase FYN | Homo sapiens | View |
| Melanocortin receptor 1 | Homo sapiens | View |
| Urokinase-type plasminogen activator | Homo sapiens | View |
| Coagulation factor VII | Homo sapiens | View |
| Leukocyte common antigen | Homo sapiens | View |
| Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform | Homo sapiens | View |
| Sodium/hydrogen exchanger 5 | Homo sapiens | View |
| Matriptase | Homo sapiens | View |
| Vitamin K-dependent protein C | Homo sapiens | View |
| Kallikrein 1 | Homo sapiens | View |
| Cytochrome P450 2E1 | Homo sapiens | View |
| Cytochrome P450 2A6 | Homo sapiens | View |
| Homo sapiens | Homo sapiens | View |
| Caco-2 | Homo sapiens | View |
| Gastric inhibitory polypeptide receptor | Homo sapiens | View |
| Vasoactive intestinal polypeptide receptor 1 | Homo sapiens | View |
| Amiloride-sensitive cation channel 3 | Homo sapiens | View |
| Solute carrier family 22 member 1 | Homo sapiens | View |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | View |
| Plasma | Homo sapiens | View |
| Bile salt export pump | Homo sapiens | View |
| Thrombin | Homo sapiens | View |
| Plasminogen | Homo sapiens | View |
| Adenosine deaminase | Homo sapiens | View |
| Plasma kallikrein | Homo sapiens | View |
| HMG-CoA reductase | Homo sapiens | View |
| Trypsin I | Homo sapiens | View |
| Histamine H2 receptor | Homo sapiens | View |
| Calcitonin receptor | Homo sapiens | View |
| Amiloride-sensitive sodium channel alpha-subunit | Homo sapiens | View |
| Equilibrative nucleoside transporter 1 | Homo sapiens | View |
| Cysteinyl leukotriene receptor 1 | Homo sapiens | View |
| Adenosine A2a receptor | Homo sapiens | View |
| Cathepsin D | Homo sapiens | View |
| Melanocortin receptor 4 | Homo sapiens | View |
| GABA-B receptor 1 | Homo sapiens | View |
| Cathepsin G | Homo sapiens | View |
| C-C chemokine receptor type 4 | Homo sapiens | View |
| Neuronal acetylcholine receptor protein alpha-4 subunit | Homo sapiens | View |
| Complement C1s | Homo sapiens | View |
| Angiotensin II type 2 (AT-2) receptor | Homo sapiens | View |
| Cerebroside-sulfatase | Homo sapiens | View |
| Interleukin-8 receptor B | Homo sapiens | View |
| Corticotropin releasing factor receptor 2 | Homo sapiens | View |
| Melanocortin receptor 3 | Homo sapiens | View |
| Melanocortin receptor 5 | Homo sapiens | View |
| Motilin receptor | Homo sapiens | View |
| Sodium/hydrogen exchanger 1 | Homo sapiens | View |
| Tissue-type plasminogen activator | Homo sapiens | View |