Kallikrein 1
Target ID: CHEMBL2319
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| NAFAMOSTAT | N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)cc1 | IC50: 12000.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1ccc([16*])cc1 | 4.92 | 38 |  |
| [5*]NC(=N)N | 4.92 | 38 |  |
| [3*]O[3*] | 4.92 | 38 |  |
| [1*]C([6*])=O | 4.92 | 38 |  |
| O=C(Oc1ccc2ccccc2c1)c1ccccc1 | 4.92 | 38 |  |