Smoothened homolog
Target ID: CHEMBL5971
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ERGOCALCIFEROL | C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)/C=C/[C@H](C)C(C)C)CC[C@@H]12 | EC50: 3800.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [7*]C1CCC[C@]2(C)[C@@H]([15*])CC[C@@H]12 | 5.42 | 21 |  |
| [7*]C1C[C@@H](O)CCC1=C | 5.42 | 21 |  |
| [7*]CC[7*] | 5.42 | 21 |  |
| [7*]C[C@H](C)C(C)C | 5.42 | 21 |  |
| C=C1CCCC/C1=C/C=C1\CCCC2CCC[C@@H]12 | 5.42 | 21 |  |