Heat shock factor protein 1
Target ID: CHEMBL5869
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| RAF-265 | Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21 | Kd: 10000.0 nM |  |
| QUERCETIN | O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 | IC50: 32870.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [14*]c1cc([16*])ccn1 | 5.0 | 39 |  |
| [5*]N[5*] | 5.0 | 39 |  |
| [8*]C(F)(F)F | 5.0 | 39 |  |
| c1ccc(Nc2nc3cc(Oc4ccnc(-c5ncc[nH]5)c4)ccc3[nH]2)cc1 | 5.0 | 39 |  |
| [16*]c1ccc([16*])cc1 | 5.0 | 39 |  |