Sodium/nucleoside cotransporter 2
Target ID: CHEMBL5780
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ADENOSINE | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | Km: 42000.0 nM |  |
| FLOXURIDINE | O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F | IC50: 2.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [8*]CO | 5.13 | 46 |  |
| c1ncc2ncn([C@H]3CCCO3)c2n1 | 4.38 | 38 |  |
| [13*][C@@H]1O[C@H]([13*])[C@@H](O)[C@H]1O | 4.38 | 38 |  |
| [9*]n1cnc2c(N)ncnc21 | 4.38 | 38 |  |
| [9*]n1cc(F)c(=O)[nH]c1=O | 8.7 | 8 |  |