Histone acetyltransferase GCN5
Target ID: CHEMBL5501
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| HEXACHLOROPHENE | Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl | Control current: 237.4 % |  |
| MIFEPRISTONE | CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)C)cc3)C[C@@]21C | IC50: 0.028 nM |  |
| HALOPROGIN | Clc1cc(Cl)c(OCC#CI)cc1Cl | MIC: 3.13 ug.mL-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N(C)C | 10.55 | 31 |  |
| [15*][C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C21 | 10.55 | 31 |  |
| [16*]c1ccc([16*])cc1 | 10.55 | 31 |  |
| O=C1C=C2CC[C@@H]3C(=C2CC1)[C@@H](c1ccccc1)CC1CCC[C@H]13 | 10.55 | 31 |  |
| [8*]C[8*] | None | 23 |  |