Suppressor of fused homolog
Target ID: CHEMBL5390
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| TOZASERTIB | Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 | Ki: 0.6 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| O=C(Nc1ccc(Sc2nc(Nc3cc[nH]n3)cc(N3CCNCC3)n2)cc1)C1CC1 | 9.22 | 39 |  |
| [5*]N1CCN(C)CC1 | 9.22 | 39 |  |
| [11*]S[11*] | 9.22 | 39 |  |
| [5*]N[5*] | 9.22 | 39 |  |
| [1*]C([6*])=O | 9.22 | 39 |  |