Urokinase plasminogen activator surface receptor

Target ID: CHEMBL4883

Organism: Homo sapiens

Type: SINGLE PROTEIN

View on ChEMBL

Molecules

Name SMILES Bioactivity Structure
AMITRIPTYLINE CN(C)CCC=C1c2ccccc2CCc2ccccc21 IC50: 61.0 nM
BRINZOLAMIDE CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 Ki: 37.0 nM

Top Fragments

SMILES Avg pKi Count Structure
[4*]CCC[4*] 7.43 33
[4*]CC 7.43 33
[3*]OC 7.43 33
[5*]N[C@H]1CN([5*])S(=O)(=O)c2sc(S(N)(=O)=O)cc21 7.43 33
O=S1(=O)NCCc2ccsc21 7.43 33