Aspartyl/asparaginyl beta-hydroxylase
Target ID: CHEMBL4680030
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| MIDOSTAURIN | CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Kd: 11.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N([5*])C | 7.96 | 39 |  |
| O=C(N[C@H]1CC2O[C@H](C1)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O)c1ccccc1 | 7.96 | 39 |  |
| [16*]c1ccccc1 | 7.96 | 39 |  |
| [1*]C([6*])=O | 7.96 | 39 |  |
| [15*][C@@H]1C[C@H]2O[C@@](C)([C@@H]1[15*])n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | 7.96 | 39 |  |