Protein cereblon/Epidermal growth factor receptor
Target ID: CHEMBL4523680
Organism: Homo sapiens
Type: PROTEIN-PROTEIN INTERACTION
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| CANERTINIB | C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 | IC50: 74.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N1CCOCC1 | 7.13 | 39 |  |
| [16*]c1ccc(F)c(Cl)c1 | 7.13 | 39 |  |
| [5*]N[5*] | 7.13 | 39 |  |
| [1*]C(=O)C=C | 7.13 | 39 |  |
| c1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)cc1 | 7.13 | 39 |  |