Beta-glucosidase cytosolic
Target ID: CHEMBL3865
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| DUVOGLUSTAT | OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O | IC50: 91900.0 nM |  |
| MIGALASTAT | OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O | Ki: 34000000.0 nM |  |
| ANDROGRAPHOLIDE | C=C1CC[C@@H]2[C@](C)(CO)[C@H](O)CC[C@@]2(C)[C@@H]1C/C=C1/C(=O)OC[C@H]1O | IG50: 30.0 uM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [8*]CO | 2.75 | 117 |  |
| C1CCNCC1 | 2.75 | 78 |  |
| [13*][C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O | 4.04 | 39 |  |
| [13*][C@H]1NC[C@H](O)[C@@H](O)[C@H]1O | 1.47 | 39 |  |
| [7*]C1C(=O)OC[C@H]1O | None | 39 |  |