Protein-tyrosine phosphatase 2C
Target ID: CHEMBL3864
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| CAFFEIC ACID | O=C(O)/C=C/c1ccc(O)c(O)c1 | IC50: 1200000.0 nM |  |
| ESTRADIOL | C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O | IC50: 1.5 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| c1ccccc1 | 2.92 | 39 |  |
| [16*]c1ccc(O)c(O)c1 | 2.92 | 39 |  |
| [7*]CC(=O)O | 2.92 | 39 |  |
| [7*]C[8*] | 2.92 | 39 |  |
| C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O | 8.82 | 29 |  |