Aurora kinase B/Inner centromere protein
Target ID: CHEMBL3430907
Organism: Homo sapiens
Type: PROTEIN COMPLEX
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| INAMRINONE | Nc1cc(-c2ccncc2)c[nH]c1=O | Mean ED50: 0.389 mg kg-1 |  |
| MILRINONE | Cc1[nH]c(=O)c(C#N)cc1-c1ccncc1 | Mean ED50: 0.037 mg kg-1 |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| O=c1ccc(-c2ccncc2)c[nH]1 | None | 62 |  |
| [16*]c1ccncc1 | None | 62 |  |
| [16*]c1cc(C#N)c(=O)[nH]c1C | None | 39 |  |
| [16*]c1c[nH]c(=O)c(N)c1 | None | 23 |  |