Target ID: CHEMBL261
Organism: Homo sapiens
Type: SINGLE PROTEIN
Name | SMILES | Bioactivity | Structure |
---|---|---|---|
HISTIDINE | N[C@@H](Cc1c[nH]cn1)C(=O)O | KA: 4.0 uM | ![]() |
DORZOLAMIDE | CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 | Ki: 50000.0 nM | ![]() |
HISTAMINE | NCCc1c[nH]cn1 | KA: 2.0 uM | ![]() |
ACETAZOLAMIDE | CC(=O)Nc1nnc(S(N)(=O)=O)s1 | Ki: 250.0 nM | ![]() |
TOPIRAMATE | CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1 | Ki: 250.0 nM | ![]() |
DICHLORPHENAMIDE | NS(=O)(=O)c1cc(Cl)c(Cl)c(S(N)(=O)=O)c1 | Ki: 1200.0 nM | ![]() |
MAFENIDE | NCc1ccc(S(N)(=O)=O)cc1 | Ki: 25000.0 nM | ![]() |
VALDECOXIB | Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1 | Ki: 54000.0 nM | ![]() |
SULFANILAMIDE | Nc1ccc(S(N)(=O)=O)cc1 | Ki: 28000.0 nM | ![]() |
PHENYLALANINE | N[C@@H](Cc1ccccc1)C(=O)O | Solubility: 245000.0 ug.mL-1 | ![]() |
POLAPREZINC | NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O | KA: 1.3 uM | ![]() |
ETHOXZOLAMIDE | CCOc1ccc2nc(S(N)(=O)=O)sc2c1 | Ki: 25.0 nM | ![]() |
BRINZOLAMIDE | CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 | Ki: 37.0 nM | ![]() |
ASPARTIC ACID | N[C@@H](CC(=O)O)C(=O)O | KA: 48.0 uM | ![]() |
INDISULAM | NS(=O)(=O)c1ccc(S(=O)(=O)Nc2cccc3c(Cl)c[nH]c23)cc1 | Ki: 30.0 nM | ![]() |
METHAZOLAMIDE | CC(=O)/N=c1/sc(S(N)(=O)=O)nn1C | Ki: 50.0 nM | ![]() |
SMILES | Avg pKi | Count | Structure |
---|---|---|---|
c1ccccc1 | 5.03 | 138 | ![]() |
[14*]c1c[nH]cn1 | None | 106 | ![]() |
c1c[nH]cn1 | None | 106 | ![]() |
[4*]CC | 6.38 | 102 | ![]() |
[5*]N[5*] | 7.04 | 101 | ![]() |