Amyloid-beta A4 protein
Target ID: CHEMBL2487
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| GENTIAN VIOLET | CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1.[Cl-] | Lysis: 100.0 % |  |
| CONGO RED | Nc1c(/N=N/c2ccc(-c3ccc(/N=N/c4cc(S(=O)(=O)[O-])c5ccccc5c4N)cc3)cc2)cc(S(=O)(=O)[O-])c2ccccc12.[Na+].[Na+] | Kd: 1500.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [16*]c1ccc(/N=N/c2cc(S(=O)(=O)[O-])c3ccccc3c2N)cc1 | 5.82 | 39 |  |
| c1ccc2cc(/N=N/c3ccc(-c4ccc(/N=N/c5ccc6ccccc6c5)cc4)cc3)ccc2c1 | 5.82 | 39 |  |
| [7*]C([8*])[8*] | None | 22 |  |
| [5*]N(C)C | None | 22 |  |
| [7*]C1C=CC(=[N+](C)C)C=C1 | None | 22 |  |