Sodium channel alpha subunit
Target ID: CHEMBL2331043
Organism: Homo sapiens
Type: PROTEIN FAMILY
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| MIBEFRADIL | COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C | Inhibition: 86.0 % |  |
| AMITRIPTYLINE | CN(C)CCC=C1c2ccccc2CCc2ccccc21 | IC50: 61.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| c1ccc2c(c1)CCC(CCNCCCc1nc3ccccc3[nH]1)C2 | None | 39 |  |
| [3*]OC | None | 39 |  |
| [4*]CCC[8*] | None | 39 |  |
| [4*]CC[8*] | None | 39 |  |
| [1*]C(=O)C[4*] | None | 39 |  |