Histamine N-methyltransferase
Target ID: CHEMBL2190
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| DABIGATRAN | Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccn3)ccc21 | IC50: 9.3 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [14*]c1nc2cc([16*])ccc2n1C | 8.03 | 38 |  |
| O=C(Nc1ccccn1)c1ccc2[nH]c(CNc3ccccc3)nc2c1 | 8.03 | 38 |  |
| [16*]c1ccc(C(=N)N)cc1 | 8.03 | 38 |  |
| [14*]c1ccccn1 | 8.03 | 38 |  |
| [5*]N[5*] | 8.03 | 38 |  |