Carbonic anhydrase V
Target ID: CHEMBL2111457
Organism: Homo sapiens
Type: PROTEIN FAMILY
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ACETAZOLAMIDE | CC(=O)Nc1nnc(S(N)(=O)=O)s1 | Ki: 250.0 nM |  |
| DICHLORPHENAMIDE | NS(=O)(=O)c1cc(Cl)c(Cl)c(S(N)(=O)=O)c1 | Ki: 1200.0 nM |  |
| ETHOXZOLAMIDE | CCOc1ccc2nc(S(N)(=O)=O)sc2c1 | Ki: 25.0 nM |  |
| TOPIRAMATE | CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1 | Ki: 250.0 nM |  |
| METHAZOLAMIDE | CC(=O)/N=c1/sc(S(N)(=O)=O)nn1C | Ki: 50.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [14*]c1nnc(S(N)(=O)=O)s1 | 6.6 | 35 |  |
| [1*]C(C)=O | 6.6 | 35 |  |
| [5*]N[5*] | 6.6 | 35 |  |
| c1nncs1 | 6.6 | 35 |  |
| NS(=O)(=O)c1cc(Cl)c(Cl)c(S(N)(=O)=O)c1 | 5.92 | 35 |  |