Serine/threonine-protein kinase AKT
Target ID: CHEMBL2111353
Organism: Homo sapiens
Type: PROTEIN FAMILY
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ZD-4190 | COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1ccnn1 | IC50: 700.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [4*]CC[8*] | 6.15 | 39 |  |
| [9*]n1ccnn1 | 6.15 | 39 |  |
| [14*]c1ncnc2cc([16*])c([16*])cc12 | 6.15 | 39 |  |
| [5*]N[5*] | 6.15 | 39 |  |
| c1ccc(Nc2ncnc3cc(OCCn4ccnn4)ccc23)cc1 | 6.15 | 39 |  |