Cyclin-dependent kinase 4/cyclin D
Target ID: CHEMBL2095942
Organism: Homo sapiens
Type: PROTEIN COMPLEX GROUP
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| BMS-387032 | CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1 | IC50: 48000.0 nM |  |
| ALVOCIDIB | CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 | IC50: 330.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [8*]C(C)(C)C | 4.32 | 39 |  |
| [14*]c1cnc([14*])o1 | 4.32 | 39 |  |
| O=C(Nc1ncc(SCc2ncco2)s1)C1CCNCC1 | 4.32 | 39 |  |
| [11*]S[11*] | 4.32 | 39 |  |
| [5*]N[5*] | 4.32 | 39 |  |