Carbonic anhydrase
Target ID: CHEMBL2095180
Organism: Homo sapiens
Type: PROTEIN FAMILY
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ACETAZOLAMIDE | CC(=O)Nc1nnc(S(N)(=O)=O)s1 | Ki: 250.0 nM |  |
| METHAZOLAMIDE | CC(=O)/N=c1/sc(S(N)(=O)=O)nn1C | Ki: 50.0 nM |  |
| ETHOXZOLAMIDE | CCOc1ccc2nc(S(N)(=O)=O)sc2c1 | Ki: 25.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [14*]c1nnc(S(N)(=O)=O)s1 | 6.6 | 35 |  |
| [1*]C(C)=O | 6.6 | 35 |  |
| [5*]N[5*] | 6.6 | 35 |  |
| c1nncs1 | 6.6 | 35 |  |
| [4*]CC | 7.6 | 33 |  |