Solute carrier family 22 member 5
Target ID: CHEMBL2073693
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| FUROSEMIDE | NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl | Ki: 100000.0 nM |  |
| EMETINE | CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc21 | IC50: 40.0 nM |  |
| AMPICILLIN | CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O | MIC: 5.0 ug.mL-1 |  |
| POLAPREZINC | NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O | KA: 1.3 uM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N[5*] | 4.0 | 68 |  |
| [6*]C(=O)O | 4.0 | 34 |  |
| c1c[nH]cn1 | None | 34 |  |
| [1*]C(=O)CCN | None | 34 |  |
| [4*][C@@H](C[8*])C(=O)O | None | 34 |  |