Sulfonylurea receptor 2
Target ID: CHEMBL1971
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| CROMAKALIM | CC1(C)Oc2ccc(C#N)cc2C(N2CCCC2=O)C1O | IC50: 1100.0 nM |  |
| PINACIDIL ANHYDROUS | CC(N/C(=N\C#N)Nc1ccncc1)C(C)(C)C | IC50: 800.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| CC1(C)Oc2ccc(C#N)cc2C(N2CCCC2=O)C1O | 5.96 | 39 |  |
| O=C1CCCN1C1CCOc2ccccc21 | 5.96 | 39 |  |
| [16*]c1ccncc1 | 6.1 | 39 |  |
| c1ccncc1 | 6.1 | 39 |  |
| [4*]C(C)C(C)(C)C | 6.1 | 39 |  |