CDGSH iron-sulfur domain-containing protein 1
Target ID: CHEMBL1795168
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| FUROSEMIDE | NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl | Ki: 100000.0 nM |  |
| FURAZOLIDONE | O=C1OCCN1/N=C/c1ccc([N+](=O)[O-])o1 | MIC: 77400.0 nM |  |
| BOSUTINIB | COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl | IC50: 1.3 nM |  |
| DORZOLAMIDE | CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 | Ki: 50000.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [5*]N[5*] | 7.02 | 63 |  |
| [4*]CCC[4*] | 8.89 | 39 |  |
| [3*]O[3*] | 8.89 | 39 |  |
| [3*]OC | 8.89 | 39 |  |
| [16*]c1cc([16*])c(Cl)cc1Cl | 8.89 | 39 |  |