Tyrosyl-DNA phosphodiesterase 1
Target ID: CHEMBL1075138
Organism: Homo sapiens
Type: SINGLE PROTEIN
Molecules
| Name | SMILES | Bioactivity | Structure |
|---|---|---|---|
| ATENOLOL | CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 | Pc: 1000000.0 cm s-1 |  |
| SEMAXANIB | Cc1cc(C)c(/C=C2\C(=O)Nc3ccccc32)[nH]1 | IC50: 700.0 nM |  |
Top Fragments
| SMILES | Avg pKi | Count | Structure |
|---|---|---|---|
| [14*]c1[nH]c(C)cc1C | 6.15 | 39 |  |
| O=C1Nc2ccccc2/C1=C/c1ccc[nH]1 | 6.15 | 39 |  |
| [7*]C1C(=O)Nc2ccccc21 | 6.15 | 39 |  |
| [7*]C[8*] | 6.15 | 39 |  |
| [8*]CC(N)=O | None | 16 |  |